TTrialCraft

Phase 1 PK / Safety Explorer FREE

Enter your dose cohort data to visualize dose-exposure relationships, safety signals across dose levels, and identify the optimal Phase 2 dose range. Designed for first-in-human and dose-escalation programs.

📋
Quick-Start Scenarios
Oncology (mAb)
CNS (Small Molecule)
Rare Disease (Peptide)
Custom Data
💊
Dose Cohort Data
Cohort Dose (mg) N Cmax (ng/mL) AUC0-24 t1/2 (h) AE Rate (%) Gr 3+ AE (%)

Dose-Exposure Relationship (Cmax)

Dose-Exposure Relationship (AUC)

Safety Profile by Dose

Therapeutic Index

🔥
Safety Signal Heatmap
🎯
Phase 2 Recommended Dose Range
Disclaimer: This tool is for exploratory planning and educational purposes only. It does not replace formal pharmacometric modeling or regulatory-grade analyses. All outputs are simulated estimates based on user-provided summary data. Not intended for regulatory submission.